Is redirecting a large number of domains suspicious?

[postlink]http://mattcuttsvideos.blogspot.com/2009/02/is-redirecting-large-number-of-domains.html[/postlink]http://www.youtube.com/watch?v=a70ygsHgvMwendofvid
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On February 26, 2009, Google software engineer Matt Cutts collected questions on Google Moderator and answered many of them on video.

cweave from Dallas, TX asked:

When permanently redirecting (301) a large number of domains (read: more than 10) to 1 domain does Google flag this as suspicious? What considerations does Google look at? For the purposes of this question let's assume this is a consolidation move.

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